A Review On Analytical Methods For Determination of Losartan Potassium And Pioglitazone In Different Dosage Form
Abstract
Losartan Potassium, Pioglitazone, UV Spectroscopy, Different Chromatography (HPLC, HPTLC, LC).
Nowadays antihypertensive drugs like Losartan Potassium and Antidiabetic drugs like Pioglitazone represent the first choice in the treatment of patients with type 2 diabetic nephropathy. Losartan Potassium reduced the degree of proteinuria while Pioglitazone act as efficient insulin sensitizers. Generally the Combination of Losartan Potassium and Pioglitazone are used for patients suffering from the diabetes mellitus which leads to end stage renal disease. This article narrates different chromatographic (HPLC, HPTLC, LC) & different Spectrophotometric method (UV) for Statin class single drug as well as combination with other drug. Thus, this paper will help in the selection and development of proper analytical methodologies for estimation of Losartan Potassium and Pioglitazone to achieve satisfactory results.
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