A Review: Synthesis And Docking Study of Biologically Active Esters
A. P. Rajput* & Sonali A. Patil*
From many years chemists have been taking interests in synthesizing different kinds of ester derivatives due to their increasing medicinal importance. Lots of newer ester derivatives have different biological activities such as anticancer, antioxidant, anti-inflammatory, antituberculosis, antimicrobial, antifungal etc. Chemists have prepared different bioactive ester drugs by using various methods and also carried out molecular modeling in silico of ester drug candidates with proteins (receptor) to predict bonding interactions of ester drugs with proteins responsible for that particular disease using computational methods. By finding all the results from docking one can predict the biological activities of the compounds under the study.
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