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Analytical Structures in Pharmacogenomics | Abstract

Asian Journal of Pharmaceutical Technology and Innovation (ajpti)

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Analytical Structures in Pharmacogenomics

Abstract

Kiran Kumar Vangara

Genomic studies are producing large databases of molecular information on cancers and other cell and tissue types. Hence, we have the opportunity to link these accumulating data to the drug discovery processes. Our previous efforts at 'information-intensive' molecular pharmacology have focused on the relationship between patterns of gene expression and patterns of drug activity. In the present study, we take the process a step furtherrelating gene expression patterns, not just to the drugs as entities, but to approximately 27,000 substructures and other chemical features within the drugs.

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