GET THE APP

Development and Validation RP-HPLC Method For Simultaneous Estimation of Cefuroxime Axetil and Linezolid In Combined Dosage Form | Abstract

Asian Journal of Pharmaceutical Technology and Innovation (ajpti)

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Development and Validation RP-HPLC Method For Simultaneous Estimation of Cefuroxime Axetil and Linezolid In Combined Dosage Form

Abstract

Kinjal A. Patel*, Jignesh S. Shah1, Dilip G. Maheshwari2

A simple, specific and accurate Reverse Phase High Performance Liquid Chromatography Method was developed for the simultaneous determination of Cefuroxime Axetil and Linezolid in combined dosage form. The using Kromasil C-8 (250×4.6 mm, 5 μm) column in Isocratic mode, with Mobile Phase Acetonitrile : Phosphate buffer, pH=4.0 (60:40 % v/v) (pH 4.0 adjusted with Orthophosphoric acid). The Flow Rate was 0.9 ml/min and effluents were monitored at 268 nm. The Retention Time of were found to be Linezolid and Cefuroxime Axetil 6.860 min and 8.840 min respectively. The Linearity for Cefuroxime Axetil and Linezolid were found to be 2.5-12.5 μg/ml and 3-15 μg/ml respectively. The Recoveries of Cefuroxime Axetil and Linezolid were found to be 101.66 – 101.90% and 98.14 - 101.15 % respectively. The proposed method was validated and successfully applied for the estimation of Cefuroxime Axetil and Linezolid in combined dosage form.

Share this article

tempobet

tempobet giriş

tempobet giriş

paper.io

agar io

wowcappadocia.com cappadocia tours
cappadocia-hotels.com cappadocia hotels
caruscappadocia.com cappadocia hotel
brothersballoon.com cappadocia balloon
balloon-rides.net cappadocia balloon flights

wormax io