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Gold Nanoparticles (AuNPs) and Their Anticancer Applications Leukaemia T-cells

Abstract

Yashvant Rao

NPs of metals such as gold is a field of interest for researchers in the last few decades because of their chemical, biological, biomedical, anticancer, chemotherapeutic and drug delivery properties that are expressively different from the properties of bulk materials. Au NPs play an important role in biomedicine due to their ability to inhibit/cytotoxicity cell growth in media as well as in water treatment due to their ability to attach pollutants and aggregate into large composites. The significance of Au NPs is result of their nano size and large surface area in to volume ratio. The PEs for Au NPs synthesis was prepared out of dried plant resources collected from nearby places/market. Flower and leaves of (Basil) Ocimum tenuiflorum, flowers of (Neem) Azadirachta indica, leaves of (Mentha) Mentha spicata and peel of (orange fruits) Citrussinensis extracts acted as reducing agent for HAuCl4 to Au0 to Au NPs. The salts, 99.9%, were procured from Sigma– Aldrich and other chemicals were of analytical grade and used without further purification. The 1.0 millimolar (mM) HAuCl4/AgNO3 aqueous solution was prepared using Millipore water of 5 cm-1. In this method Au NPs were synthesised by single step process at RT. For this purpose biological resources (hazardless) were used for Au NPs synthesis.

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