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In vivo Targeting of Liposomally complexed DNA Vaccines to Dendritic Cells induce Long Lasting Protection against Melanoma Tumor | Abstract

Asian Journal of Pharmaceutical Technology and Innovation (ajpti)

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In vivo Targeting of Liposomally complexed DNA Vaccines to Dendritic Cells induce Long Lasting Protection against Melanoma Tumor

Abstract

Gopi Krishna Moku

Background: Since Dendritic cells (DCs) are responsible for both in the instigation  of adaptive immune response and the tolerance initiation, manipulation of DCs with DNA vaccines in vivo encoding tumor-associated antigens is considered as an efficient approach to combat cancer [1].

 

Objective: Developing a simple & economical in vivo DCs targeting delivery system as well as achieving long-lasting immunity which is a substantial scientific task in DNA vaccination [2].

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