Liposphere - Lipid Based Drug Delivery System :A Review | Abstract

Asian Journal of Pharmaceutical Technology and Innovation (ajpti)

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Liposphere - Lipid Based Drug Delivery System :A Review


Wattamwar Mayur Madhukarrao*,Ratnaparkhi Mukesh P, Chaudhari Shilpa P

 New chemical entities (NCEs) in modern discovery libraries and

development programs have an ever-increasing number of
unconventional physical and chemical properties. In particular, up
to 70% of discovery compounds and 40% of pipeline candidates are
insoluble in water. These promising molecules present unique
formulation and development challenges and often suffer from poor
bioavailability. Therefore, conventional formulation systems
cannot be employed. Techniques available for scientists to increase
the bioavailability of poorly soluble drugs are either increasing
their solubility in biological media of choice, or increasing their
dissolution kinetics. The use of advanced lipid-based drug delivery
systems (LBDDS) is a strategy to design pharmaceutical dosage
forms with improved therapeutic benefits.

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