Asian Journal of Pharmaceutical Technology and Innovation (ajpti)

Molecular Imprinting: An Emerging Technology

Abstract

Jesika Rane*, Priyanka Adhikar, Dr. R.L. Bakal

This article gives the recent developments in molecular imprinting for proteins. Currently bio-macromolecules such as antibodies and enzymes are mainly employed for protein recognition purposes. However, such bio-macromolecules are sometimes difficult to find and/or produce, therefore, receptor-like synthetic materials such as protein-imprinted polymers have been intensively studied as substitutes for natural receptors. Recent advances in protein imprinting shown here demonstrate the possibility of this technique as a future technology of protein recognition. This review summarizes the previous and current literature regarding the analytical tools employed for characterization of synthesized MIPs. It is our expectation that this will facilitate researchers to plan their own sophisticated analytical pathway for characterization of MIPs in a more logical and structured fashion, and to begin to appreciate the limitations of the present approaches in this molecularly complex area.

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