Monoclonal Antibodies Present New Opportunities in Disease Diagnosis and Treatment
Abstract
Monoclonal Antibodies Present New Opportunities in Disease Diagnosis and Treatment
The production of MAbs by hybridoma technology was discovered in 1975 by Georges Kohler of West Germany and Cesar Milstein of Argentina. Who developed a technique to fuse splenocyte cells (separated from the spleen of an immunized mouse) with tumorous myeloma cells., our vision for antibodies as tools for research for prevention, detection and treatment of diseases, vaccine production, antigenic characterization of pathogens and in the study of genetic regulation of immune responses and disease susceptibility has been revolutionized. Recently, MAbs have been widely applied in the field of clinical medicine. They are also used in the tissue typing, enzyme linked immunosorbent assay, radio immunoassay, immunological intervention with passive antibody, or magic bullet therapy with cytotoxic agents coupled with anti-mouse specific antibody.
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