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Study on Protective Effect of Omega -3 Fatty Acid Rich Extract of Linium Usitatissimum Seeds on Cisplatin Induced Nephrotoxicity | Abstract

Asian Journal of Pharmaceutical Technology and Innovation (ajpti)

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Study on Protective Effect of Omega -3 Fatty Acid Rich Extract of Linium Usitatissimum Seeds on Cisplatin Induced Nephrotoxicity

Abstract

Priyanka Saini*

 There are many diseases that are still considered as untreatable by

most of the physicians, and epilepsy is one of those. Traditional
healers claim that they can treat epilepsy by use of some natural
components. The Indian Traditional Medicine like Ayurveda, Siddha
and Unani are predominantly based on the use of herbal drugs/
products for medicinal benefits. Herbal drugs have gained
importance and popularity in recent years because of their safety,
efficacy and cost effectiveness. One of the important and welldocumented
uses of plant products is their use as nephro-protective
agents. Hence, there is an ever increasing need for safe nephroprotective
agent.
Oxidative stress is a state where oxidative forces exceed the
antioxidant systems due to loss of the balance between them. Thus
due to easy availability of plant and its traditional uses, the present
study was designed to investigate the effect of plant extract against
Cisplatin induced nephrotoxicity in rats by using biochemical
parameters and antioxidant status in kidney of rats after oral
administration of 100 and 200 mg/ kg body weight of extract.

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