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Asian Journal of Pharmaceutical Technology and Innovation (ajpti)

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Airemwen C.O

Dr, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Benin, Nigeria

Publications

  • Research Article   
    Formulation of an Optimised Glimepiride Compression Coated Tablets for Chronotherapeutic Drug Delivery
    Author(s): Airemwen C.O*, Uhumwangho M.U and Obakpolor S.O

    Background: Chronopharmaceutics is an aspect of pharmaceutics devoted to the formulation of drug delivery systems that release their active ingredients at a rhythm that ideally matches the physiological requirement of a particular disease condition. Objective: The aim of the present study is to formulate an optimized coated glimepiride time release tablets (CGTRT) containing glimepiride, a third generation sulphonylurea in the inner core for chronotherapeutic drug delivery system. Method: Glimepiride core tablets (GCT) containing Anacardium occidentale gum (10 %w/w) as binder and maize starch as disintegrant (10 %w/w) were prepared at compression pressure of 30 unit on the arbitrary load scale. CGTRT containing Anacardium occidentale gum powder with sodium starch glycolate at varying concentration (0.5%, 1%, 2%, 4%, and 6%w/w) were also prepared at 30 unit.. Read More»

    Abstract HTML PDF

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